abstract：:Selective oestrogen receptor modulators are a range of compounds which mimic some, but not all, agonist actions of oestrogen in different tissues. They were developed with the aim of maximizing the benefits of oestrogen-like drugs in a number of important conditions whilst reducing adverse side-effects. The molecular ...

journal_title：Current opinion in obstetrics & gynecology

authors： Baynes KC,Compston JE

更新日期：1998-06-01 00:00:00

abstract：:An increasing number of diseases in child and adult life are now thought to have their origins in the fetal period. Central to this predisposition is restriction of fetal growth. During the period reviewed in this article, the associations between adult hypertension and low birthweight were confirmed, and numerous stu...

journal_title：Current opinion in obstetrics & gynecology

authors： Newnham J

更新日期：1998-04-01 00:00:00

abstract：:The management of advanced ovarian cancer relies on appropriate surgical cytoreduction in conjunction with appropriate adjuvant chemotherapy. In the past year several studies have continued to support aggressive cytoreduction at the initial operation, including for stage IV disease, as well as in a second-look setting...

journal_title：Current opinion in obstetrics & gynecology

authors： Chen LM,Berek JS

更新日期：1998-02-01 00:00:00

abstract：:In contrast to the reduction in perinatal mortality in high-risk pregnancies, screening of low-risk pregnancies with umbilical artery Doppler ultrasonography has shown no benefit. Advances in pathophysiology question the assumption that the placenta is hypoxic in fetal growth restriction, with absent end-diastolic fre...

journal_title：Current opinion in obstetrics & gynecology

authors： Burrell SJ,Kingdom JC

更新日期：1997-12-01 00:00:00

abstract：:Current studies verify the safety of surgery in the elderly. Delirium is a costly complication, but its incidence and severity can be reduced by pre- and postoperative interventions. Avoidance of even mild hypothermia has now been shown to reduce cardiovascular morbidity. New information available on the cardiovascula...

journal_title：Current opinion in obstetrics & gynecology

authors： Miller KL

更新日期：1997-10-01 00:00:00

abstract：:The principles of managed care are more difficult to apply to preventive medical treatments, such as hormone replacement therapy, than to the investigation and treatment of established disease. In addition to an ageing society with increased health demands, the use of hormone replacement therapy is increasing in most ...

journal_title：Current opinion in obstetrics & gynecology

authors： Wardle PG

更新日期：1997-08-01 00:00:00

abstract：:Recent publications about emergency and implantable contraception focused on increasing the awareness about emergency contraceptive methods and on updating readers about the controversies surrounding Norplant. Both emergency and implantable contraception have excellent safety and efficacy profiles, yet neither has rea...

journal_title：Current opinion in obstetrics & gynecology

authors： Cullins VE,Garcia FA

更新日期：1997-06-01 00:00:00

abstract：:Advances in perinatal and neonatal health care over the past few decades have resulted in a substantial reduction in perinatal mortality. Some of this improvement has been attributed to antepartum fetal surveillance techniques. The primary objective of antepartum fetal surveillance techniques is to avoid fetal deaths....

journal_title：Current opinion in obstetrics & gynecology

authors： Ananth CV,Smulian JC,Vintzileos AM

更新日期：1997-04-01 00:00:00

abstract：:This review concentrates on the structural and functional aspects of lesions of the female genital tract that cause infertility, including cervical changes after treatment for neoplasia, uterine malformations, leiomyoma, endometrial aberrations, infection-related tubal lesions, ovarian disorders (oocyte defects, prema...

journal_title：Current opinion in obstetrics & gynecology

authors： Honoré LH

更新日期：1997-02-01 00:00:00

abstract：:Chronic medical problems and the various medications available to treat them represent an enormous volume of information for the practicing obstetrician. The agents commonly encountered are reviewed here and current literature is explored, where available, including the literature on folates in pregnancy. ...

journal_title：Current opinion in obstetrics & gynecology

authors： Colie CF

更新日期：1996-12-01 00:00:00

abstract：:Voiding disorders are frequently associated with urinary incontinence and other lower urinary tract dysfunction in women, but the cause of these disorders is not well understood and treatment options are limited. Little has changed in the treatment and evaluation of voiding disorders. New approaches to the study of de...

journal_title：Current opinion in obstetrics & gynecology

authors： Stevenson KR

更新日期：1996-10-01 00:00:00

abstract：:Virilization occurring in the postmenopausal woman may be either adrenal or ovarian in origin. We describe the case of a 74-year-old postmenopausal woman with severe virilization and a serum testosterone level elevated into the male range who was found to have a non-malignant aetiology for her condition. ...

journal_title：Current opinion in obstetrics & gynecology

authors： Conn JJ,Conway GS

更新日期：1996-10-01 00:00:00

abstract：:We have attempted to review the best available evidence for the commonest gynaecological endoscopic procedures. Controlled studies are the exception rather than the rule, and randomized studies are even rarer. Therefore, the results of large, uncontrolled series must be acknowledged. As a result, for most procedures, ...

journal_title：Current opinion in obstetrics & gynecology

authors： Nagele F,Molnár BG,O'Connor H,Magos AL

更新日期：1996-08-01 00:00:00

abstract：:Infertile couples who seek medical advice have one single hope: to have one or more children. Therefore, pregnancy rates per cycle of any assisted reproductive technique that include early miscarriages and ectopic pregnancies are of little interest to them. They want to know their chances of having a baby. When counse...

journal_title：Current opinion in obstetrics & gynecology

authors： Tanbo T,Abyholm T

更新日期：1996-06-01 00:00:00

abstract：:The field of preimplantation genetic diagnosis has undergone significant advances since the report of the first birth from this method in 1990. The first birth in the USA was reported in 1992, as was the first successful diagnosis and delivery of a baby free of a single gene defect disorder (cystic fibrosis and then T...

journal_title：Current opinion in obstetrics & gynecology

authors： Grifo JA,Tang YX,Munne S,Krey L

更新日期：1996-04-01 00:00:00

abstract：:Human papillomavirus-related anogenital neoplasia is an active area of basic and clinical research. The research topics are broad based, but mostly are focused on delineating the clinical utility of human papillomavirus testing, the natural history of human papillomavirus infections and associated premalignancies, cha...

journal_title：Current opinion in obstetrics & gynecology

authors： Duggan MA

更新日期：1996-02-01 00:00:00

abstract：:The value of directed management based on contemporary fetal assessment techniques in the high-risk pregnancy is undisputed. Whether such benefits are evident in the low-risk pregnancy is now an issue of considerable clinical and economic importance. Recent literature suggests that extension of fetal surveillance to t...

journal_title：Current opinion in obstetrics & gynecology

authors： Manning FA

更新日期：1995-12-01 00:00:00

abstract：:Through the study of naturally occurring mutations in humans, the creation of mutations by site-directed mutagenesis, and the production of transgenic knockout mice, further understanding of molecular reproductive endocrinology had been achieved. Mutations in the aromatase gene in females have confirmed that its defic...

journal_title：Current opinion in obstetrics & gynecology

authors： Layman LC

更新日期：1995-10-01 00:00:00

abstract：:The failure to store urine resulting from bladder outflow incompetence requires a method to increase outflow resistance. Peri- and intraurethral injection is one form of treatment capable of accomplishing this need. The best results are obtained in those women who do not have detrusor abnormalities, who have adequate ...

journal_title：Current opinion in obstetrics & gynecology

authors： Appell RA

更新日期：1995-10-01 00:00:00

abstract：:Laparoscopic oophorectomy is one of the most controversial and challenging areas of endoscopic surgery. Judicious preoperative evaluation along with careful patient selection can reduce the risk of operating on an unsuspected ovarian malignancy. Appropriate patient consent and planning should be obtained before the pr...

journal_title：Current opinion in obstetrics & gynecology

authors： Russell JB

更新日期：1995-08-01 00:00:00

abstract：:Human embryo cryopreservation is now a fully established adjunct to assisted reproduction, with thawed embryos implanting at a rate approaching that of fresh embryos. As with fresh embryos, the quality of frozen-thawed embryos is affected by patient age at the time of oocyte retrieval, and by culture conditions. Ovari...

journal_title：Current opinion in obstetrics & gynecology

authors： Tucker MJ,Morton PC,Sweitzer CL,Wright G

更新日期：1995-06-01 00:00:00

abstract：:Transvaginal ultrasonography is emerging as the newest method for the early detection of structural malformations and markers of chromosomal aberrations. According to a multicenter registry on the onset of fetal anomalies, many defects are potentially detectable at an early transvaginal scan. Moreover, cystic hygroma ...

journal_title：Current opinion in obstetrics & gynecology

authors： Rottem S

更新日期：1995-04-01 00:00:00

abstract：:Approximately 2-3% of cervical smears will be reported as showing low-grade changes. Many of these smears are in fact associated with high-grade cervical intraepithelial neoplasia requiring treatment, but a significant number will be associated with an absence of cervical intraepithelial neoplasia, where surveillance ...

journal_title：Current opinion in obstetrics & gynecology

authors： Cruickshank ME,Kitchener HC

更新日期：1995-02-01 00:00:00

abstract：:For the majority of women, gynecologic cancer is a survivable disease. A brief overview of the recent findings on the psychological and behavioral aspects of gynecologic cancer is provided. The discussion is organized by disease-relevant time points, from prevention to recovery or death. Recognition of the positive re...

journal_title：Current opinion in obstetrics & gynecology

authors： Andersen BL

更新日期：1995-02-01 00:00:00

abstract：:The obstetrician-gynecologist must assume a dual role in the future provision of health care to women. Not only should the obstetrician-gynecologist function as a consultant for medical and surgical problems peculiar to the female reproductive tract, but also assume a broader-based role for preventive medicine and hea...

journal_title：Current opinion in obstetrics & gynecology

authors： Laube DW

更新日期：1994-12-01 00:00:00

abstract：:The proper use of forceps or vacuum extractor, or both, remains a safe and effective modality in achieving the universal goal of a healthy mother and baby. Their use requires continued experience, sharing of information, and possibly attention to subtleties of design. This review looks at the current situation with sp...

journal_title：Current opinion in obstetrics & gynecology

authors： Robinson JC

更新日期：1994-10-01 00:00:00

abstract：:Doppler ultrasound velocimetry of uteroplacental, umbilical, and fetal vessels provides the clinician with important information on the hemodynamics of the vascular area under study. Transvaginal color Doppler is a new technique that allows precise investigation of fetomaternal circulation in early pregnancy. Doppler ...

journal_title：Current opinion in obstetrics & gynecology

authors： Kurjak A,Kupesic S,Zudenigo D

更新日期：1994-10-01 00:00:00

abstract：:Pelvic floor dysfunction, specifically urinary and fecal incontinence, is thought to be widespread. Prevalence figures for these disorders vary greatly. This review highlights the accepted prevalence and incidence figures for pelvic floor dysfunction and their relative age distribution in women. Remission and natural ...

journal_title：Current opinion in obstetrics & gynecology

authors： Mallett VT,Bump RC

更新日期：1994-08-01 00:00:00

abstract：:During the past year much effort has been focused on defining the DNA content of gestational trophoblastic tumors. Flow cytometric and image analysis studies of molar pregnancies confirmed that the majority of partial hydatidiform moles were triploid, and, as expected, most complete hydatidiform moles were diploid or ...

journal_title：Current opinion in obstetrics & gynecology

authors： Lage JM

更新日期：1994-08-01 00:00:00

abstract：:Minimally invasive surgery enables the avoidance of, preparation for, participation in, and treatment of complications following assisted reproductive technology (ART). The major recent changes are, the development of surgical techniques to diagnose and treat intrafallopian tubal abnormalities; the use of operative en...

journal_title：Current opinion in obstetrics & gynecology

authors： Wood C

更新日期：1994-06-01 00:00:00

abstract：:The corpus luteum is controlled by luteinizing hormone (LH) and intraovarian morphofunctional specialization and autocrine/paracrine mechanisms. Corpus luteal insufficiency produces luteal phase defects (LPD). The poor precision and validation of endometrial histologic dating and single or random multiple serum proges...

journal_title：Current opinion in obstetrics & gynecology

authors： Dawood MY

更新日期：1994-04-01 00:00:00

abstract：:Recent advances in seemingly remote areas of investigation, i.e. yeast cell cycle research and DNA amplifications, have opened spectacular avenues for understanding reproduction. The new insights on the single cell and subcellular level of processes, such as egg maturation, sperm-egg interaction and implantation enhan...

journal_title：Current opinion in obstetrics & gynecology

authors： Zilberstein M,Seibel MM

更新日期：1994-04-01 00:00:00

abstract：:The most important papers address controversial aspects of fetal cardiology, for example, screening for congenital heart disease (CHD), the diagnosis and the accuracy of diagnosis, and the management of fetal tachycardias. There are some interesting additions to the literature although some conclusions require further...

journal_title：Current opinion in obstetrics & gynecology

authors： Allan LD

更新日期：1994-02-01 00:00:00

abstract：:Child sexual abuse is being recognized as a common and serious problem which affects children regardless of their age, sex, socio-economic class, or geographic location. Children of all ages, from infancy to young adulthood, have been victims of abuse. It is well accepted that the number of reported incidents of child...

journal_title：Current opinion in obstetrics & gynecology

authors： Muram D

更新日期：1993-12-01 00:00:00

abstract：:During the past few years enormous progress has been made in the understanding of the molecular mechanisms involved in parturition; however, the answer to the fundamental question of how labor is initiated remains elusive. This is a very important question because alterations in the timing of birth (preterm and post-t...

journal_title：Current opinion in obstetrics & gynecology

authors： Valenzuela GJ,Germain A,Foster TC

更新日期：1993-10-01 00:00:00

abstract：:Loss of pelvic support involving the 'middle compartment' is manifested by herniation through the central pelvic floor in proximity to the intersection of an imaginary line from the public symphysis to the coccyx with another from one ischial spine to opposite ischial spine. Loss of middle compartment support may exis...

journal_title：Current opinion in obstetrics & gynecology

authors： Timmons MC,Addison WA

更新日期：1993-08-01 00:00:00

abstract：:Urinary tract infections (UTIs) are still one of the most common bacterial infections in pregnant and non-pregnant women. It is estimated that about 10-20% of all women suffer from a UTI at some point in life. The presence of UTI is defined as the existence of urinary symptoms such as frequency of urination and dysuri...

journal_title：Current opinion in obstetrics & gynecology

authors： Weissenbacher ER,Reisenberger K

更新日期：1993-08-01 00:00:00

abstract：:The advent of the AIDS epidemic coupled with enhanced recognition of the morbidity and mortality associated with occupationally acquired hepatitis B virus infection has resulted in a great interest in the epidemiologic characteristics of contact of surgical personnel with patient's blood and other bodily fluids in ass...

journal_title：Current opinion in obstetrics & gynecology

authors： Hemsell DL

更新日期：1993-06-01 00:00:00

abstract：:Ultrasound prenatal diagnosis of structural anomalies has become almost a separate branch of obstetrics. The advantages of performing ultrasound in pregnancies at high risk for fetal structural anomalies are clear. Patients and the news media have placed ever-increasing expectations on persons performing diagnostic ul...

journal_title：Current opinion in obstetrics & gynecology

authors： Gomez KJ,Copel JA

更新日期：1993-04-01 00:00:00

abstract：:In the past decade, neoadjuvant and concomitant multimodality therapies have been studied in patients with cervical cancer. The past year has witnessed more pilot studies confirming the feasibility of multimodality therapy. It is now time to move to prospective randomized clinical trials to determine the effects on di...

journal_title：Current opinion in obstetrics & gynecology

authors： Runowicz CD,Smith HO,Goldberg GL

更新日期：1993-02-01 00:00:00